Predicting and Taming Immunogenicity: Strategies for your Biologic Drug
Immunogenicity is the ability of a foreign substance, such as a drug or vaccine, to provoke an immune response. While provoking immunogenicity is a desired outcome for vaccines, the development of anti-drug antibodies (ADAs) can inactivate a biologic drug’s therapeutic effects and potentially cause safety issues. The issue of immunogenicity imposes both scientific and regulatory … Continued