Concentration-QT (C-QT) modeling has been conducted for multiple compounds at various stages of development in different therapeutic areas. Data from available single and multiple ascending-dose (SAD/MAD) studies were pooled to construct population C-QT models, with post hoc predictions of concentration from a pharmacokinetic model.
十一月 1, 2009
Author(s): Shashank Rohatagi, Timothy Carrothers, Jonathan Wagg, Tatiana Khariton
Year: 十一月 1, 2009
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