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ACoP11

ACoP11
Speakers & Posters
Integration of Omics Data Sources to Inform Mechanistic Modeling of Immune-Oncology Therapies
Dr Andrzej Kierzek | Head of Systems Modelling/Simcyp
Integration of Omics Data Sources to Inform Mechanistic Modeling of Immune-Oncology Therapies (no description)
Cotton Rat Modelling and Validation with Model Based Meta-Analysis (MBMA) for RSV
Jos Lommerse, Director of Modeling & Simulation; Michelle Green, Executive Director, COS-IDD; Nele Mueller-Plock, Director, COS-IDD; Li Qin, Scientist, COS-IDD; Gerly van der Vleuten, Scientist, COS-IDD; Marianne van Vugt, Associate Scientist, COS-IDD; Anna Largajolli, Associate Director, COS-IDD; S. Y. Amy Cheung, Sr. Director, COS-IDD |
Poster ID: TUE-043 - Cotton Rat Modelling and Validation with Model Based Meta-Analysis (MBMA) for RSV
Population PBPK Modeling using the Quasi-Random Parametric EM Algorithm
Janak Wedagedera, Sr Research Scientist R&D; Frederic Bois, Sr. Science Investigator,Head of Mechanistic Modeling; Anthonia Afuape, Research Scientist; Siri Kalyan Chirumamilla, Research Scientist; Hiroshi Momiji, Sr. Research Scientist; Robert Leary, Consultant; Mike Dunlavey, Consultant; Richard Matthews, Sr. Software Developer; Khaled Abduljalil, Sr. Scientist; Masoud Jamei, SVP, R&D |
Poster ID: TUE-026 - Fitting Population PBPK models with Quasi Random Parametric EM Algorithm (QRPEM) and the Nonparametric Adaptive Grid Method (NPAG) of the Simcyp Simulator and comparison with Bayesian MCMC and HMCMC
Population pharmacokinetics modeling of Brincidofovirand the active metabolite cidofovirdiphosphate in healthy volunteers
Jie (Janet) Zhou, Scientist, Consulting Services; Camila de Almeida, Associate Director, COS-IDD; Nathan Teuscher, Vice President, COS-IDD; Virna Schuck, Sr. Director, COS-IDD |
Poster ID: TUE-040 - Population pharmacokinetics modeling of Brincidofovir and the active metabolite cidofovirdiphosphate in healthy volunteers
ACoP 11 Welcome & Opening Remarks
Dr Craig Comisar | ACoP11 Scientific Committee Chair/Senior Director of Pharmacometrics, Certara
A Bayesian Population Compartmental Absorption and Transit Modeling Approach to Support Generic Drug Development and Regulation Application to Bupropion
Nan Hung Hsieh, Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University; Frederic Y. Bois, Sr Science Investigator, Head of Mechanistic Modeling |
Poster ID: TUE-059 - A Bayesian Population Compartmental Absorption and Transit Modeling Approach to Support Generic Drug Development and Regulation Application to Bupropion
A minimal brain PBPK model to support the preclinical development of antibody therapeutics for neurlogical diseases
Peter Bloomingdale, Suruchi Bakshi, Cesar Pichardo-Almarza, Christian Maass, Eline van Maanen, Piet van der Graaf, Nitin Mehrotra |
QSP for COVID: repurposing and combining models and drugs
Piet can der Graaf | SVP QSP, Certara
Applying Pharmacometrics and Model-Informed Drug Development (MIDD) to Global Health Challenges
Dr Mark Lovern | SVP, Quantitative Science Services, COS-IDD
Applying Pharmacometrics and Model-Informed Drug Development (MIDD) to Global Health Challenges (no description)
Applying Pharmacometrics and Model-Informed Drug Development (MIDD) to Global Health Challenges
Dr Felix Boakye-Agyeman | Director, COS-IDD
Applying Pharmacometrics and Model-Informed Drug Development (MIDD) to Global Health Challenges (no description)
Quantifying the Quality of Antimalarial Drugs in Ghana
Dr Felix Boakye-Agyeman | Director, COS-IDD
Quantifying the Quality of Antimalarial Drugs in Ghana (no description)
State of the Art in Bayesian Methods for Mechanistic PBPK and QSP Models: Concepts and Applications
Dr Frederic Bois | Sr Sci Advisor & Head of Mechanistic Modelling, R&D
State of the Art in Bayesian Methods for Mechanistic PBPK and QSP Models: Concepts and Applications (no description)
Bayesian Meta-Analysis for Pharmacokinetic Parameters
Dr Witold Wiecek | Consultant, Decision Analytics
Bayesian Meta-Analysis for Pharmacokinetic Parameters (no description)
How to be Very Discrete, Yet Smoothly Effective: Use of Published Discrete Trial Endpoint Data to Optimize Trial Designs
Dr. Jos Lommerse | Director Modeling & Simulation
How to be Very Discrete, Yet Smoothly Effective: Use of Published Discrete Trial Endpoint Data to Optimize Trial Designs
Implementation of gamma distributed delays through a fast ODE approach
Shuhua Hu, Principle Research Scientist; Michael Tomashevskiy, R&D Consultant |
Poster ID: THU-072 - Implementation of gamma distributed delays through a fast ODE approach
Population Pharmacokinetics of Heptanoate in Healthy Volunteers and Patients with Long-Chain Fatty Acid Oxidation Disorders (LC-FAOD) Treated with Triheptanoin
Nathalie H Gosselin, Sr. Director, COS-IDD; Claudia Jomphe, Director, COS-IDD |
Poster ID: WED-060 - Population Pharmacokinetics of Heptanoate in Healthy Volunteers and Patients with Long-Chain Fatty Acid Oxidation Disorders (LC-FAOD) Treated with Triheptanoin
Population Pharmacokinetics (PopPK) and Concentration-QTc (C-QTc) Analysis of DS-1062, a TROP2 Directed Antibody Drug Conjugate (ADC), in Patients With Non–small Cell Lung Cancer (NSCLC)
Yasong LU, Quantitative Clinical Pharmacology, Daiichi Sankyo, Inc.; Bill Poland, Vice President, COS-IDD; Kashyap Patel, Director, COS-IDD; Helen Kastrissios, Vice President, COS-IDD; Stefanie Hennig, Associate Director, COS-IDD |
Poster ID: THU-092 - Population Pharmacokinetics (PopPK) and Concentration-QTc (C-QTc) Analysis of DS-1062, a TROP2 Directed Antibody Drug Conjugate (ADC), in Patients With Non–small Cell Lung Cancer (NSCLC)
Model Informed target selection and validation through combining quantitative systems pharmacology (QSP) with network-based analysis (NBA)
Viji Chelliah, Principle Scientist, QSP; Piet van der Graaf, SVP, Quantitative Systems Pharmacology |
Poster ID: THU-084 - Model Informed target selection and validation through combining quantitative systems pharmacology (QSP) with network-based analysis (NBA)
ALWAYS Count Your Chickens before They Hatch: Optimizing trial design for Quantitative Decision-Making
Dr Nele Mueller-Plock | Director Pharmacometrics
ALWAYS Count Your Chickens before They Hatch: Optimizing trial design for Quantitative Decision-Making
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